ニュース

2016年09月28日 掲載 (Published 09/28/2016)


「Biophysics and Physicobiology」に Koutaro Nakagome et al. “Model simulation of the SPOC wave in a bundle of striated myofibrils”を掲載

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Koutaro Nakagome, Katsuhiko Sato, Seine A.Shintani, Shin’ichi Ishiwata
“Model simulation of the SPOC wave in a bundle of striated myofibrils”

【Significance】
Model simulation of the SPOC wave in a bundle of striated myofibrils

SPOC (SPontaneous Oscillatory Contraction) is a phenomenon observed in striated muscle under the intermediate activation conditions. To understand the SPOC properties in a bundle of myofibrils, we have extended the single myofibril model to a two-dimensional (2D) and a three-dimensional (3D) model, in which myofibrils are elastically connected side-by-side through cross-linkers between the Z-lines and the M-lines. These models could reproduce various patterns of SPOC waves experimentally observed in a bundle of myofibrils by choosing appropriate values of elastic constants of the cross-linkers and external spring.

Biophysics and Physicobiology, Vol.13, pp. 217-226

URL:https://www.jstage.jst.go.jp/article/biophysico/13/0/13_217/_article