「Biophysics and Physicobiology」〈Special Issue: "Memorial Issue for Prof. Nobuhiko Saitô"〉に Motonori Ota et al. “Itinerary profiling to analyze a large number of protein-folding trajectories”を掲載

2016年11月22日 学会誌

日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が新規掲載されました。

Motonori Ota, Mitsunori Ikeguchi, Akinori Kidera
“Itinerary profiling to analyze a large number of protein-folding trajectories”

【Significance】
Itinerary profiling and network methods identify characteristic folding pathways of Trp-cage

Recent advances in computer technology now enable the performance of large-scale molecular dynamics simulations. As a result, a large number of protein-folding trajectories can be generated to be analyzed in detail. We have developed an itinerary profiling method to process trajectory data. The profiling and network methods were applied to the Trp-cage data and the characteristic folding pathways were determined. It demonstrates that these techniques are powerful tools which can be used to decipher the complex dynamical data of bio-molecules.

Biophysics and Physicobiology, Vol.13, pp. 295-304


URL:https://www.jstage.jst.go.jp/article/biophysico/13/0/13_295/_article

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