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Story of the Cover

Progress of theoretical and computational biophysics—in honor of Professor Nobuhiro Go’s outstanding contribution on the occasion of his 80th birthday

(Mikio Kataoka, Akio Kitao, Hidetoshi Kono, Biophysics and Physicobiology 16, 173-175 (2019), DOI: 10.2142/biophysico.16.0_173)

This figure symbolizes the tools and fruits of theoretical and computational protein biophysics: Two fundamental equations are tools for protein dynamics and for the second derivative calculation of energy function. The upper right represents the lattice model developed by Professor Nobuhiro Go (Go model), which is widely used for the theoretical studies of protein folding. Energy landscape of native protein conformation is rather rugged and jumping-among-minima motions are origins of protein anharmonicity. Normal modes distributed over BPTI (lower left) revealed how protein is oscillating.


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