「Biophysics and Physicobiology」に Ichiro Yamato et al. “Operating principles of rotary molecular motors: differences between F₁ and V₁ motors”を掲載

2016 March 11 BPPB

日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が新規掲載されました。

Ichiro Yamato, Yoshimi Kakinuma and Takeshi Murata　
“Operating principles of rotary molecular motors:
differences between F₁ and V₁ motors”

【Significance】
Molecular rotation mechanism of rotary motors

V- and F-ATPases are unique molecular rotary motors among many types of bioenergy-transducing machineries. We recently reported the crystal structures of the bacterial V_1-ATPase, corresponding to an intermediate state of waiting for ATP hydrolysis in the catalytic cycle. Rotary dynamics and torque generation of same V_1-ATPase have also been revealed. Based on these results of crystal structures and single-molecule observations, we present a novel V_1-ATPase rotational mechanism model that is apparently different from that of F_1-ATPases.


Biophysics and Physicobiology, Vol.13, pp. 37-44

URL:https://www.jstage.jst.go.jp/article/biophysico/13/0/13_37/_article

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