「Biophysics and Physicobiology」にRyotaro Koike et al. “All Atom Motion Tree detects side chain-related motions and their coupling with domain motion in proteins”を掲載
2019 November 29 BPPB
日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が新規掲載されました。
Ryotaro Koike, Motonori Ota “All Atom Motion Tree detects side chain-related motions and their coupling with domain motion in proteins”
【Significance】
All atom motion tree
To detect small and large structural changes in proteins we have developed All Atom Motion Tree (AAMT), which compares distinct structures of a protein using all heavy atoms including side chains. AAMT identified a number of side chain-related (SCR) motions in addition to domain motions. We analyzed coupling of domain and SCR motions in many proteins. The statistics indicate that couplings among SCR motions are common, as are those of SCR and domain motions. Our results demonstrate that AAMT is a useful tool to evaluate the coupling of local and global motions and their consistency with protein function.
Biophysics and Physicobiology, Vol.16, 280-286
URL:https://doi.org/10.2142/biophysico.16.0_280
