An article with the title "Ionic strength-sensitive and pH-insensitive interactions between C-reactive protein (CRP) and an anti-CRP antibody" by Yuka Oka, Shota Ushiba, Naruto Miyakawa, Madoka Nishio, Takao Ono, Yasushi Kanai, Yohei Watanabe, Shinsuke Tani, Masahiko Kimura, Kazuhiko Matsumoto is published.
2022 February 26 BPPB
A following article is published in "Biophysics and Physicobiology".
Yuka Oka, Shota Ushiba, Naruto Miyakawa, Madoka Nishio, Takao Ono, Yasushi Kanai, Yohei Watanabe, Shinsuke Tani, Masahiko Kimura, Kazuhiko Matsumoto
"Ionic strength-sensitive and pH-insensitive interactions between C-reactive protein (CRP) and an anti-CRP antibody"
【Significance】
As C-reactive protein (CRP) is an important biomarker of infection and inflammation, demand exists for highly sensitive, rapid, and low-cost immunosensors. When designing biosensors, understanding the environmental effects such as pH and ionic strength change is important, because they significantly affect the binding affinity. The results of this study are useful for developing CRP sensors.
Biophysics Physicobiology, 2022, Volume 19, Article ID: e190003
URL:https://doi.org/10.2142/biophysico.bppb-v19.0003
