News

An article with the title "Structural overview of the translocase of the mitochondrial outer membrane complex" by Yuhei Araiso, Toshiya Endo is published.

2022 June 30 BPPB

A following article is published in "Biophysics and Physicobiology".

Yuhei Araiso, Toshiya Endo
"Structural overview of the translocase of the mitochondrial outer membrane complex"

【Significance】
The TOM complex in the mitochondrial outer membrane functions as the main entry gate for the import of ~1,000 different mitochondrial proteins synthesized in the cytosol into mitochondria. Recent progress in cryo-electron microscopy with single particle analyses allowed us to determine high-resolution structures of the TOM complex, which, in combination with structure-based biochemical analyses, led to revealing significant insight into the molecular mechanisms of the precise as well as efficient import of mitochondrial proteins with divergent chemical and physical properties.

Biophysics Physicobiology, 2022, Volume 19, Article ID: e190022



URL:https://doi.org/10.2142/biophysico.bppb-v19.0022



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