ニュース

2018年03月07日 掲載 (Published 03/07/2018)


「Biophysics and Physicobiology」にKeisuke Arikawa “Theoretical framework for analyzing structural compliance properties of proteins ”を掲載

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Keisuke Arikawa “Theoretical framework for analyzing structural compliance properties of proteins”

【Significance】
Structural compliance analysis of proteins

We propose methods for directly analyzing structural compliance (SC) properties of the elastic network models of proteins, methods for extracting information about the motion properties from the SC properties, and methods for quantitatively evaluating the motion properties. Under the assumption that the softer motions occur easily, we can obtain information about the motion properties, including the allosteric interactions between the specified parts, by decomposing the motion according to the magnitude of SC (SC mode decomposition). As application examples, we have analyzed lactoferrin and ATCase. The results show that we can understand their motion properties using their softer motions.


Biophysics and Physicobiology, Vol.15, pp. 58-74

URL:https://www.jstage.jst.go.jp/article/biophysico/15/0/15_58/_article