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「Biophysics and Physicobiology」にKoichi Nakajo “Gating modulation of the KCNQ1 channel by KCNE proteins studied by voltage-clamp fluorometry”を掲載

2019年05月24日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Koichi Nakajo “Gating modulation of the KCNQ1 channel by KCNE proteins studied by voltage-clamp fluorometry”

【Significance】
Voltage-clamp fluorometry on KCNQ1 channels

Voltage clamp fluorometry (VCF) is a powerful tool to track conformational rearrangement of the voltage sensor domain (VSD) of voltage-gated ion channels. The KCNQ1 channel is a voltage-gated potassium channel and its gating properties are largely dependent on which types of auxiliary KCNE proteins bind. Recent applications of VCF to KCNQ1 channel have started to reveal the mechanisms in which KCNE proteins modulate the VSD movement and the gating properties of the KCNQ1 channels.


Biophysics and Physicobiology, Vol.16, 121-126
URL:https://doi.org/10.2142/biophysico.16.0_121


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