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「Biophysics and Physicobiology」にMikio Kataoka et al. “Mechanism of the light-driven proton pump of bacteriorhodopsin based on the consistency principle”を掲載

2019年11月29日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Mikio Kataoka, Hironari Kamikubo “Mechanism of the light-driven proton pump of bacteriorhodopsin based on the consistency principle”

【Significance】
Proton pump of bR with consistency principle

In this paper, we expand on the consistency principle, originally proposed to explain protein structure formation, to explain the light-driven proton pumping mechanism of bacteriorhodopsin. We propose that consistency-breaking is a trigger for protein function, and that the rearrangement of intramolecular interactions to establish new consistency or restore the original consistency provides the driving force for function. This hypothesis is applicable to other functional proteins that have two distinct conformers. Thus, the consistency principle provides general principles for understanding complex systems.

Biophysics and Physicobiology, Vol.16, 274-279
URL:https://doi.org/10.2142/biophysico.16.0_274


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