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「Biophysics and Physicobiology」にArina Afanasyeva et al. “Prediction of the secondary structure of short DNA aptamers”を掲載

2019年11月29日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Arina Afanasyeva, Chioko Nagao, Kenji Mizuguchi “Prediction of the secondary structure of short DNA aptamers”

【Significance】
Prediction of the secondary structure of short DNA aptamers

DNA aptamers have many applications in biotechnology. In particular, they demonstrated the great ability as sensors of the protein surface, which can be helpful for the design of highly selective inhibitors of protein-protein interactions. The structure of the protein-aptamer complex is necessary for this kind of analysis, although most of the nucleic acid structure modelling programs are originally designed for RNA. In this study, we present the first attempt to assess the accuracy of three secondary structure predicting tools in application to DNA aptamers.

Biophysics and Physicobiology, Vol.16, 287-294
URL:https://doi.org/10.2142/biophysico.16.0_287


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