ニュース

「Biophysics and Physicobiology」にKazuhiro Takemura et al. “More efficient screening of protein-protein complex model structures for reducing the number of candidates”を掲載

2019年11月29日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Kazuhiro Takemura, Akio Kitao “More efficient screening of protein-protein complex model structures for reducing the number of candidates”

【Significance】
Efficient screening of docking model structure

We proposed an efficient screening method to decrease the number of protein-protein complex model structures (decoys) using a relatively simple clustering method. By applying our approach to the decoys generated by the rigid-body docking method, ZDOCK, we reduced the number of decoys by 93% compared to ZDOCK in terms of the number of decoys containing at least one near-native decoy with 90% probability. After clustering using the fraction of common contacts, the top 1,000 success rate (defined as the rate having at least one near-native model in the selected decoys) reached 97%.

Biophysics and Physicobiology, Vol.16, 295-303
URL:https://doi.org/10.2142/biophysico.16.0_295


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