ニュース

「Biophysics and Physicobiology」にMiki Nakano et al. “Parameter optimization for 3D-reconstruction from XFEL diffraction patterns based on Fourier slice matching”を掲載

2019年11月29日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Miki Nakano, Osamu Miyashita, Florence Tama “Parameter optimization for 3D-reconstruction from XFEL diffraction patterns based on Fourier slice matching”

【Significance】
Parameter optimization for 3D-reconstruction from XFEL diffraction patterns based on Fourier slice matching

In this study, we examined the effect of data binning on the resolutions of restored 3D-molecular structures from the 2D-diffraction images obtained by X-ray Free Electron Laser (XFEL) single particle analysis. We found that the advantage of pixel binning on reducing noise exceeds the disadvantage of losing the detailed pixel information, and that the interpolation parameters should be optimized in relation to binning size. By using an optimal parameter set, a lower linear oversampling ratio of around four is sufficient to restore the 3D-molecular structure by single particle analysis using XFEL experiments.

Biophysics and Physicobiology, Vol.16, 367-376
URL: https://doi.org/10.2142/biophysico.16.0_367


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