ニュース

「Biophysics and Physicobiology」にNobuhiko Kajinami et al. “Polymer brush in articular cartilage lubrication: Nanoscale modelling and simulation”を掲載

2019年11月29日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Nobuhiko Kajinami, Mitsuhiro Matsumoto “Polymer brush in articular cartilage lubrication: Nanoscale modelling and simulation”

【Significance】
Polymer brush in articular cartilage lubrication: Nanoscale modelling and simulation

Full atom modelling and molecular dynamic simulations of ionic polymer systems are presented to investigate lubrication mechanism of articular cartilage, as an example of molecular simulation study in biomechanics. We use chondroitin 6-sulfate molecules grafted on resilient surface as the polymer brush and water with sodium ions as the synovial liquid. With this model, we carried out a series of molecular dynamics simulation and analyzed how polymer brush and synovial fluid affect the lubrication under constant shear. Polymers have large deformation and the flow of synovial fluid becomes deviate from the Coutette flow, leading to a drastic reduction of friction.

Biophysics and Physicobiology, Vol.16, 466-472
URL:https://doi.org/10.2142/biophysico.16.0_466


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