ニュース

「Biophysics and Physicobiology」に Akihiko Nakamura, Kei-ichi Okazaki, Tadaomi Furuta, Minoru Sakurai, Jun Ando, Ryota Iino による“Crystalline chitin hydrolase is a burnt-bridge Brownian motor”を掲載

2020年07月10日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が公開されました。

Akihiko Nakamura, Kei-ichi Okazaki, Tadaomi Furuta, Minoru Sakurai, Jun Ando, Ryota Iino “Crystalline chitin hydrolase is a burnt-bridge Brownian motor”

【Significance】
Molecular motors need ATP or a chemical potential as the bias of moving direction. The major moving mechanisms are “power stroke” and “Brownian ratchet”, and these two mechanisms are mixed in many cases. In this study, we revealed that a chitin hydrolase is a pure “burnt-bridge” Brownian ratchet motor, which creates a forward bias by shortening of the rail and inhibition of the backward movement. From the viewpoint of application, chitin is the second most abundant biomaterial on the Earth. Therefore, revealing the chitin degradation mechanism of chitinase is helpful to improve the utilization of chitin.

Biophysics and Physicobiology, Vol.17, pp51-58
URL:https://doi.org/10.2142/biophysico.BSJ-2020004


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