ニュース

2016年11月22日 掲載 (Published 11/22/2016)


「Biophysics and Physicobiology」〈Special Issue: "Memorial Issue for Prof. Nobuhiko Saitô"〉に Masaki Sasai et al. “Cooperativity and modularity in protein folding”を掲載

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Masaki Sasai, George Chikenji, Tomoki P. Terada
“Cooperativity and modularity in protein folding”

【Significance】
Cooperativity and modularity in protein folding

Statistical mechanical models have made a significant contribution to elucidating the physics of protein folding.In particular, a simple theoretical model proposed by Wako and Saitô has explained quantitative features of pathways, transition-state ensembles, and intermediates of folding of a variety of proteins. This review explains how the physical principles of protein folding were revealed by this model, and discusses the application of the model to the folding of multi-domain proteins with topologically complex conformations and to the problems in allosteric transitions.

Biophysics and Physicobiology, Vol.13, pp. 281-293

URL:https://www.jstage.jst.go.jp/article/biophysico/13/0/13_281/_article