ニュース

2017年08月23日 掲載 (Published 08/23/2017)


「Biophysics and Physicobiology」にMikihiro Shibata et al. “High-speed atomic force microscopy imaging of live mammalian cells”を掲載

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が新規掲載されました。

Mikihiro Shibata, Hiroki Watanabe, Takayuki Uchihashi, Toshio Ando, Ryohei Yasuda “High-speed atomic force microscopy imaging of live mammalian cells”

【Significance】
This paper reviews improvements for visualizing morphological dynamics of live mammalian cells by using high-speed atomic force microscopy.

Visualization of morphological dynamics of live mammalian cells with nanometer resolution under physiological conditions is highly desired. In this review, we demonstrated that the unprecedented AFM movies show nanometer-scale morphogenesis of filopodia, membrane ruffles, pit formations and endocytosis in living COS-7 and HeLa cells and hippocampal neurons with temporal resolution of seconds. We believe that this method will lead to a great advance in analysis of cellular morphogenesis and have a great impact on a wide range of biological sciences.


Biophysics and Physicobiology, Vol.14, pp.127-135

URL:https://www.jstage.jst.go.jp/article/biophysico/14/0/14_127/_article