ニュース

「Biophysics and Physicobiology」に Satoshi Toda による“Synthetic tissue engineering: Programming multicellular self-organization by designing customized cell-cell communication”を掲載

2020年07月10日 学会から

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が公開されました。

Satoshi Toda “Synthetic tissue engineering: Programming multicellular self-organization by designing customized cell-cell communication”

【Significance】
Recent advances in synthetic biology allow us to create artificial genetic programs that encode customized cell-cell communication in mammalian systems. Using this technology, we can design and test what kind of cell-cell communication can drive self-organization of cells into complex tissue structures. Our results show the flexibility and power of the modular synthetic system to program the formation of various multicellular structures. Such synthetic biology efforts on multicellular self-organization will improve our understanding of design principles of tissue development and provide new capabilities to engineer complex tissues and organoids with desired shapes and functions.

Biophysics and Physicobiology, Vol.17, pp42-50
URL:https://doi.org/10.2142/biophysico.BSJ-2020002


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