ニュース

「Biophysics and Physicobiology」に Kyoko Shinzawa-Itoh, Kazumasa Muramoto による "Biochemical and crystallographic studies of monomeric and dimeric bovine cytochrome c oxidase" を掲載

2021年08月19日 学会誌

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が公開されました。

Kyoko Shinzawa-Itoh, Kazumasa Muramoto
"Biochemical and crystallographic studies of monomeric and dimeric bovine cytochrome c oxidase"

【Significance】
Structural analyses of mitochondrial CcO have been based on the crystal structure of dimeric form. However, recent studies have revealed the structures of the monomeric form and of the monomer in the respiratory supercomplex. Characterization of the three states of CcO (the independent monomer, the monomer in the supercomplex, and the dimer) and structural and functional comparison of monomeric and dimeric CcOs suggest the mechanism of dimerization and supercomplex formation, and imply that the three states are in equilibrium and transition among these states regulates respiratory electron transport activity.

Biophysics Physicobiology, 2021, Volume 18, Pages 186-195



URL:https://doi.org/10.2142/biophysico.bppb-v18.020


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