Biophysics and Physicobiology論文賞

日本生物物理学会では、Biophysics and Physicobiologyに掲載された論文のうち、生物物理学並びにBiophysics and Physicobiology誌に貢献した功績に対し、「Biophysics and Physicobiology論文賞」を贈っています。

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第14回Biophysics and Physicobiology 論文賞

　会誌65巻1号および学会ウェブサイトにて会員の皆様にご推薦をお願いした第14回Biophysics and Physicobiology 論文賞受賞論文が決定いたしましたので，ここにお知らせします．

Takeharu Sekiguchi, Shingo Sotoma and Yoshie Harada
Fluorescent nanodiamonds as a robust temperature sensor inside a single cell.
BPPB vol. 15, pp. 229-234 (2018)

【授賞理由】

The temperature sensing ability of commonly used fluorescence-based sensors is easily affected by environmental factors, which has been a major concern in real bio-applications. In the Sekiguchi study, they demonstrated that the temperature sensing ability of a new type of temperature sensor, fluorescent nanodiamonds with negatively charged nitrogen vacancy centers, is almost unaffected by environmental factors such as pH, ion concentration, viscosity, molecular interactions, and organic solvents. This robustness makes fluorescent nanodiamonds a reliable thermometer even in complex biological cellular environments. Furthermore, the simple protocol developed here to measure the absolute temperature inside a single cell using a single fluorescent nanodiamond enables intracellular temperature measurement with an accuracy better than ±1°C.
Thus, this is an outstanding paper that presents a highly valuable, precise, and broadly applicable method for measuring temperature inside a single cell, and it is expected to facilitate further advancements across various scientific disciplines.

2025年6月
Biophysics and Physicobiology 論文賞選考委員会