「Biophysics and Physicobiology」にYutaro Yamada et al. “Demonstration of correlative atomic force and transmission electron microscopy using actin cytoskeleton”を掲載

2017年07月28日 学会誌

日本生物物理学会欧文誌［Biophysics and Physicobiology］に以下の論文が新規掲載されました。

Yutaro Yamada, Hiroki Konno, Katsuya Shimabukuro
“Demonstration of correlative atomic force and transmission electron microscopy using actin cytoskeleton”

【Significance】
Bridging atomic force microscopy with transmission electron microscopy

We report a new microscopy technique called correlative atomic force and transmission electron microscopy (correlative AFM/TEM) in which a targeted region of a sample can be observed under both AFM and TEM. Recent advances in AFM have allowed detailed observation of the dynamic nature of biomolecules. However, specifying molecular species by AFM alone still remains a challenge. We demonstrate correlative AFM/TEM using actin filaments, and further show that immune electron microscopy to specify molecules can be integrated into this technique. Thus, correlative AFM/TEM could be a versatile method to investigate complex biological systems at the molecular level.


Biophysics and Physicobiology, Vol.14, pp.111-117
https://www.jstage.jst.go.jp/article/biophysico/14/0/14_111/_article

URL:https://www.jstage.jst.go.jp/article/biophysico/14/0/14_111/_article

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