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「Biophysics and Physicobiology」に Takayoshi Tsubo による "Analysis of the mechanism of synaptic integration focusing on the charge held in the spine" を掲載

2021年12月18日 学会誌

日本生物物理学会欧文誌[Biophysics and Physicobiology]に以下の論文が公開されました。

Takayoshi Tsubo
"Analysis of the mechanism of synaptic integration focusing on the charge held in the spine"

【Significance】
In this study, it was clarified that high reproducibility of synaptic integration is achieved by propagating the polarization of the medium adjacent to the charge held in each spine and adding it to raise the membrane potential. Furthermore, using the approach of this study, it was possible to clarify that spine neck capacitance and spine head size contribute significantly to synaptic integration, that distant spines are able to contribute to synaptic integration, that a single neuron is able to integrate a large number of input combinations, and that inhibitory post-synapses on dendrites effectively suppress the success of synaptic integration.

Biophysics Physicobiology, 2021, Volume 18, Pages 290-304


URL: https://doi.org/10.2142/biophysico.bppb-v18.036



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